Secondary Structural Analysis of Families of Protein Sequences using Chaos Game Representation

نویسندگان

  • K. Manikandakumar
  • K. Gokul Raj
  • S. Muthukumaran
  • R. Srikumar
چکیده

CGR is an effective method for visualizing any structural features if it is given as a sequence of elements [1,2] analyzed by the genomic signature appears as a powerful tool for investigating the mechanisms of DNA maintenance from which the DNA structure results. It would be necessary to understand the patterns they exhibit and to be able to interpret them in a biologically meaningful way [3]. All informational macromolecules of biological interest are linear polymers. The subsequences of a genome exhibit the main characteristics of the whole genome, attesting to the validity of the genomic signature concept [2]. A great extent concentration has newly been focused on analyzing the biological sequences of both Deoxyribo Nucleic Acid (DNA) and proteins using the patterns observed in their graphical representations [1-9] and mathematical descriptions. These studies have shown applications in chemo informatics and bioinformatics. Chaos Game Representation (CGR) for gene (or DNA) sequences was introduced by [4,5] the underlying structures of genome sequences of a few model organisms that were obtained using CGR plots. CGR also offers new possibilities to resolve scale dependencies for information content in sequences [7].

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تاریخ انتشار 2012